@Mitchinator9339 wrote on Twitter: "Dec did such a good job on #SaturdayNightTakeaway tonight".
Ant is, of course, now back in rehab following his vehicle crash and subsequent drink-driving charge last month.
The live Saturday night entertainment show will return to TV tonight and the biggest part of the show is the live audience.
Scarlett Moffatt and Stephen Mulhern will be on hand in their regular support roles.
On Friday Dec revealed he was heading for rehearsals solo in a message on Twitter. "Night y'all. D X".
There's been much speculation over the past few days as to whether Dec will address Ant when he hosts the show alone, as it was reported that "show chiefs have been agonising over whether Dec should apologise for Ant's no-show, ignore the incident or have no mention of Ant at all".More news: More than 150 kids attend annual egg hunt at township park
More news: Astronomers perplexed to find that distant galaxy has no dark matter
More news: Netflix orders King Arthur reimagining series Cursed
Ant was charged with drink-driving following a collision on March 18, and is expected to appear in court on April 4.
Donnelly will present next week's final episode in Florida.
An insider from the show has revealed to The Sun that explaining the 42-year-old's absence has been the most hard aspect of planning for this week's show.
This will be the first time in 20 years that Dec has had to present without Ant by his side, so he's understandably feeling the pressure ahead of tonight's show.
The source added that producers are anxious that a "sombre start" will affect the show, as it is all meant to be about having fun.
Fans twetted: "It's Davina and Decs #saturdaynighttakeaway by the look of things!'; '@antanddec @ThisisDavina Dec and Davina I'm in tears"; "Ah yes, I love that show called Davina and Dec's Saturday Night Takeaway"; '#SaturdayNightTakeaway so its Dec and Davina (oh Ant)'.
Next weekend's Takeaway will be live from Universal Studios Orlando for the series finale.