The Syrian president added that the threats endanger global peace and security and that military action would only contribute to the "further destabilization" of the region.
"We have not declared war on the regime of Bashar al-Assad", Macron said in the interview.
This spring, Macron's government began implementing plans to tax retirees more and employees less, cut jobs in some hospitals, reorganize the justice system, and apply a new university admissions system, all of which prompted protests.
Speaking today he vowed to fight against terrorism, ensure global law is upheld and added that beinging a free regime to Sryia is the only thing to ensure peace in the country.
Playing up his credibility, he ordered the French armed forces to intervene on Saturday in coordination with American and British forces to strike several Syrian targets, which were alleged by the Western powers as chemical arsenal of the Syrian government. But France appears likely to strike Syria regardless, security analysts said.
He also revealed he was in contact with President Trump, and added he wanted to avoid "escalation".
"France will not allow any escalation that could harm the stability of the region as a whole", he said Thursday, "but we can't let regimes think they can do everything they want, including the worst things that violate global law".
"So there is no practicable alternative to the use of force to degrade and deter the use of chemical weapons by the Syrian regime", May said.
France persuaded President Donald Trump to stay in Syria and launch airstrikes as punishment for an alleged chemical-weapons attack, French President Emmanuel Macron said Sunday.More news: LeBron James notches triple-double as Cavs drop Game 1 to Pacers
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While it is unusual for a French president to present himself as driving US policy in military matters in the Middle East, Macron and Trump have developed a friendly relationship over the past year.
Appearing in a two-hour live broadcast, the 40-year-old leader said the US, Britain and France had "full worldwide legitimacy to intervene" in order to enforce global humanitarian law.
The report said that for now France did not have chemical samples from the attack site analyzed by its own laboratories yet.
"Never said when an attack on Syria would take place", Trump tweeted.
Russian Federation has military forces, including air defenses, in several areas of Syria to support Assad in his long war against anti-government opposition forces.
The decision to strike Syrian government targets followed a week of hectic diplomacy and coordination with US and British allies.
"Germany will not take part in possible - there have not been any decisions yet, I want to stress that - military action", she said after meeting Danish Prime Minister Lars Lokke Rasmussen in Berlin.
"On April 7, dozens of men, women and children were massacred in Douma, with the use of a chemical weapon in a total violation of worldwide rules".