More specifically, Brighton have lost all seven away games against the big six since joining the Premier League and their only goal in those matches came in last season's 3-1 defeat against City.
And, much to Guardiola's frustration, the City manager admitted Mendy, who has played just 13 games for the club since joining from Monaco past year, arrived late for treatment and training on Sunday.
They are winless at Anfield since May 2003 - a run of 17 games in all competitions - but Guardiola said he expects his team to fight for a result.
And Guardiola insisted the attitude of his players has helped City reach the same - if not higher - heights than they did last term, a claim that will be tested in Sunday's visit to Liverpool. "With that spirit, the way we play, everybody is focused". The France worldwide has also been criticised for his social media use and has taken a break since being pictured at Anthony Joshua's fight in London last Saturday night, hours before his late appearance.
City were not expecting him to be available until late November, but his return could well come before this month's global break.
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Pep is delighted with the way his players have started the new season.
City strolled to the title last season, playing only for records over the final weeks of the season, but this campaign is shaping up differently, with Chelsea and especially Liverpool looking capable of providing a serious challenge.
Pep Guardiola's side head into the match having won their last three games.
Guardiola has confirmed Kevin De Bruyne's recovery from a knee ligament injury is progressing on schedule, with the midfielder expected to resume training in the next week or so. After the dribble, no dribble, good assist, no assist. he will improve.
"But our profession is so demanding and every single day you have to do your best and in the last two or three games he was really good. When they don't do that, after that they know what happens".